Exploration of total flavonoids, phenolic contents, antioxidant and anti-bacterial activities of Rubus fruticosus L. as a new sources of drug
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Abstract
This study was carried out in order to screen new drug candidate for many of human diseases.The study was carried out for the exploration of total flavonoids, phenolic contents,antioxidant and anto-bacterial activities of Rubus fruticosus as a new source of drug. Rubus fruticosus L. was screened for the estimation of total Flavonoid and Phenolic contents and antioxidant and anti-bacterial activities. R. fruticosus exhibited 50.01 ± 0.03 mg/100 g of alkaloids in leaf, 21.1 ± 0.07 mg/100 g in stem and 18.65 ± 0.13 mg/100 g in root. Total phenolic content (TPC) ranged from 51.02 ± 0.12 to 42.01 ± 0.08. The maximum content found in stem was 71.31 ± 0.04 mg GAE/g. Ethanol extract (EtE) of leaf, stem and root showed that the flavonoid content (TFC) of R. fruticosus extracts varied from 94.23 ± 0.10 to 47.13± 0.05 mg Rutin/g. Ethanolic extract of stem showed maximum DPPH scavenging activity (27±0.11. Above results revealed that ethanolic extract is reliable for proton-donating capability and could work, as free radical inhibitors and utilizing the plant extracts in traditional medicines can aid to cure most persistent human diseases.Keeping in view its medicinal significance with regards to community it is best suited antibacterial and antioxidant plant in order to cure many bacterial and metabolic disease. It will be a new insight for drugs screening and discovery of new compounds in order to use it for the benefit of society.
Keywords: Antibacterial; Ethanolic extract; Ethnobotany; Medicinal plants