27. Study of antimicrobial effects of honey in comparison to the antibiotics on the microbes isolated from infected burn wounds
Abstract
A study was conducted to evaluate the antimicrobial effect of fresh honey produced by Apis mellifera on the bacterial species isolated from infested burns wounds in order to compare it firstly to the antibiotics which are used for the treatment of burn infection. Secondly to assess the possible synergistic effects of bee honey when mixed to antibiotic. Blood specimens were collected with the help of cultural swap from 2-4 weeks old 30 hospitalized patients with burn infection. These blood samples were cultured on different media and four major bacterial strains including E-coli, Klebsiella spp, Staphylococcus aureus and Pseudomonas aeruginosa were isolated and antibiotic sensitivity pattern was measured against these microorganisms by using following three types of antibiotics i.e, Amikacin (AK), Zinacef (CXM), Linozolid (LZD). The result shows that honey has a significant inhibitory growth effects on Pseudomonas aeruginosa’s growth (61%) followed by E. coli (55%), Staphylococcus aureus (56%), and Klebsiella spp (25%) as compared to the antibiotics alone.
Keywords: Honey; Microbes; Zinacef; Burn wounds