23. Antimicrobial activity of Polygonium hydropiper leaves against plant and human pathogenic fungal and bacterial strains
Abstract
The present study was conducted to investigate the antimicrobial activities of Polygonium hydropiper L. leaves extract against bacteria and fungi using the disc diffusion method. The extract showed significant antibacterial activities against four strains of gram positive bacteria namely Clavibacter, Staphylococcus aureus, Lactococcous lactis and Bacillus clausii species and four strains of gram negative bacteria namely Escherichia coli, Citrobacter, Proteus and Xanthomonas species. The minimum inhibitory concentration (MIC) values against the bacterial culture were ranged from 16 to 64 ug mL-1. The antifungal activities were found against six toxic fungal strains namely Penicillium, Fusarium, Trichoderma, Aspergillus niger, Pythium, and Acremonium. It was concluded that Polygonium hydropiper methanolic leaves extract acted as an antibacterial and antifungal agent and can be used in wide range of pharmaceuticals industries. Such as Quinine was the first natural product to be produced on industrial scale for its use against malaria.
Keywords: Polygonium Hydropiper. L; Methanol Extract; Leaves; Antimicrobial; Minimum Inhibitory Concentration
